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Construction of Escherichia coli Whole-Cell Biosensors for Statin Efficacy and Production Test

Statins are widely used cholesterol-lowering drugs. Their potential application in anti-cancer treatment is also under investigation. The individual variance in statin response has been observed, which may be caused by the variation in human HMG-CoA reductase (hHMGR)—the inhibition target of statin...

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Detalles Bibliográficos
Autores principales: Li, Huanjie, Wang, Qingda, Zhao, Rui, Wang, Yunshan, Xun, Luying, Liu, Huaiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326143/
https://www.ncbi.nlm.nih.gov/pubmed/32671060
http://dx.doi.org/10.3389/fcell.2020.00404