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Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer
Coordination of gene expression with nutrient availability supports proliferation and homeostasis and is shaped by protein acetylation. Yet how physiological/pathological signals link acetylation to specific gene expression programs and whether such responses are cell-type–specific is unclear. AMP-a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326158/ https://www.ncbi.nlm.nih.gov/pubmed/32603375 http://dx.doi.org/10.1371/journal.pbio.3000732 |