Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

Coordination of gene expression with nutrient availability supports proliferation and homeostasis and is shaped by protein acetylation. Yet how physiological/pathological signals link acetylation to specific gene expression programs and whether such responses are cell-type–specific is unclear. AMP-a...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Salmerón, María, García-Martínez, José Manuel, Martínez-Useros, Javier, Fernández-Aceñero, María Jesús, Viollet, Benoit, Olivier, Severine, Chauhan, Jagat, Lucena, Silvia R., De la Vieja, Antonio, Goding, Colin R., Chocarro-Calvo, Ana, García-Jiménez, Custodia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326158/
https://www.ncbi.nlm.nih.gov/pubmed/32603375
http://dx.doi.org/10.1371/journal.pbio.3000732

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