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Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention

Naegleria fowleri is a single-cell organism living in warm freshwater that can become a deadly human pathogen known as a brain-eating amoeba. The condition caused by N. fowleri, primary amoebic meningoencephalitis, is usually a fatal infection of the brain with rapid and severe onset. Iron is a comm...

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Detalles Bibliográficos
Autores principales: Arbon, Dominik, Ženíšková, Kateřina, Mach, Jan, Grechnikova, Maria, Malych, Ronald, Talacko, Pavel, Sutak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326272/
https://www.ncbi.nlm.nih.gov/pubmed/32555641
http://dx.doi.org/10.1371/journal.pntd.0007759