Cargando…

Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development

The tumor microenvironment (TME) consists of different cell types, including tumor-associated macrophages (TAMs) and tumor-associated fibroblasts (TAFs). How these cells interact and contribute to lung carcinogenesis remains elusive. Using (G12D)KRAS- and (V600E)BRAF-driven mouse lung models, we ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamata, Tamihiro, So, Tsz Y., Ahmed, Qasim, Giblett, Susan, Patel, Bipin, Luo, Jinli, Reddel, Roger, Pritchard, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326292/
https://www.ncbi.nlm.nih.gov/pubmed/32579928
http://dx.doi.org/10.1016/j.celrep.2020.107802