Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71

PURPOSE: To study the potential effect of a gene therapy, designed to rescue the expression of dystrophin Dp71 in the retinas of Dp71-null mice, on retinal physiology. METHODS: We recorded electroretinograms (ERGs) in Dp71-null and wild-type littermate mice. In dark-adapted eyes, responses to flashe...

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Detalles Bibliográficos
Autores principales: Barboni, Mirella Telles Salgueiro, Vaillend, Cyrille, Joachimsthaler, Anneka, Liber, André Maurício Passos, Khabou, Hanen, Roux, Michel J., Vacca, Ophélie, Vignaud, Lucile, Dalkara, Deniz, Guillonneau, Xavier, Ventura, Dora Fix, Rendon, Alvaro, Kremers, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Visual Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326481/
https://www.ncbi.nlm.nih.gov/pubmed/32049345
http://dx.doi.org/10.1167/iovs.61.2.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326481/
https://www.ncbi.nlm.nih.gov/pubmed/32049345
http://dx.doi.org/10.1167/iovs.61.2.11

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