Generation of inner ear hair cells by direct lineage conversion of primary somatic cells

The mechanoreceptive sensory hair cells in the inner ear are selectively vulnerable to numerous genetic and environmental insults. In mammals, hair cells lack regenerative capacity, and their death leads to permanent hearing loss and vestibular dysfunction. Their paucity and inaccessibility has limi...

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Detalles Bibliográficos
Autores principales: Menendez, Louise, Trecek, Talon, Gopalakrishnan, Suhasni, Tao, Litao, Markowitz, Alexander L, Yu, Haoze V, Wang, Xizi, Llamas, Juan, Huang, Chichou, Lee, James, Kalluri, Radha, Ichida, Justin, Segil, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326493/
https://www.ncbi.nlm.nih.gov/pubmed/32602462
http://dx.doi.org/10.7554/eLife.55249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326493/
https://www.ncbi.nlm.nih.gov/pubmed/32602462
http://dx.doi.org/10.7554/eLife.55249

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