Vigabatrin-Induced Retinal Functional Alterations and Second-Order Neuron Plasticity in C57BL/6J Mice

PURPOSE: Vigabatrin (VGB) is an effective antiepileptic that increases concentrations of inhibitory γ-aminobutyric acid (GABA) by inhibiting GABA transaminase. Reports of VGB-associated visual field loss limit its clinical usefulness, and retinal toxicity studies in laboratory animals have yielded c...

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Detalles Bibliográficos
Autores principales: Chan, Kore, Hoon, Mrinalini, Pattnaik, Bikash R., Ver Hoeve, James N., Wahlgren, Brad, Gloe, Shawna, Williams, Jeremy, Wetherbee, Brenna, Kiland, Julie A., Vogel, Kara R., Jansen, Erwin, Salomons, Gajja, Walters, Dana, Roullet, Jean-Baptiste, Gibson, K  Michael, McLellan, Gillian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326505/
https://www.ncbi.nlm.nih.gov/pubmed/32053727
http://dx.doi.org/10.1167/iovs.61.2.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326505/
https://www.ncbi.nlm.nih.gov/pubmed/32053727
http://dx.doi.org/10.1167/iovs.61.2.17

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