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Activating Transcription Factor 3 (ATF3) Protects Retinal Ganglion Cells and Promotes Functional Preservation After Optic Nerve Crush

PURPOSE: To investigate the possible role of activating transcription factor 3 (ATF3) in retinal ganglion cell (RGC) neuroprotection and optic nerve regeneration after optic nerve crush (ONC). METHODS: Overexpression of proteins of interest (ATF3, phosphatase and tensin homolog [PTEN], placental alk...

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Detalles Bibliográficos
Autores principales: Kole, Christo, Brommer, Benedikt, Nakaya, Naoki, Sengupta, Mohor, Bonet-Ponce, Luis, Zhao, Tantai, Wang, Chen, Li, Wei, He, Zhigang, Tomarev, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326601/
https://www.ncbi.nlm.nih.gov/pubmed/32084268
http://dx.doi.org/10.1167/iovs.61.2.31