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Defective Neutrophil Function in Patients with Sepsis Is Mostly Restored by ex vivo Ascorbate Incubation

BACKGROUND: Neutrophil function is essential for effective defence against bacterial infections but is defective in patients with sepsis. Ascorbate or vitamin C, which is low in the plasma of patients with sepsis, is stored inside human neutrophils and is essential for their normal function. OBJECTI...

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Detalles Bibliográficos
Autores principales: Sae-khow, Kritsanawan, Tachaboon, Sasipha, Wright, Helen L, Edwards, Steven W, Srisawat, Nattachai, Leelahavanichkul, Asada, Chiewchengchol, Direkrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326689/
https://www.ncbi.nlm.nih.gov/pubmed/32636666
http://dx.doi.org/10.2147/JIR.S252433