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Defective Neutrophil Function in Patients with Sepsis Is Mostly Restored by ex vivo Ascorbate Incubation
BACKGROUND: Neutrophil function is essential for effective defence against bacterial infections but is defective in patients with sepsis. Ascorbate or vitamin C, which is low in the plasma of patients with sepsis, is stored inside human neutrophils and is essential for their normal function. OBJECTI...
Autores principales: | Sae-khow, Kritsanawan, Tachaboon, Sasipha, Wright, Helen L, Edwards, Steven W, Srisawat, Nattachai, Leelahavanichkul, Asada, Chiewchengchol, Direkrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326689/ https://www.ncbi.nlm.nih.gov/pubmed/32636666 http://dx.doi.org/10.2147/JIR.S252433 |
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