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ATIR101 administered after T-cell-depleted haploidentical HSCT reduces NRM and improves overall survival in acute leukemia

Overcoming graft-versus-host disease (GvHD) without increasing relapse and severe infections is a major challenge after allogeneic hematopoietic stem-cell transplantation (HSCT). ATIR101 is a haploidentical, naïve cell-enriched T-cell product, depleted of recipient-alloreactive T cells to minimize t...

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Detalles Bibliográficos
Autores principales: Roy, Denis Claude, Walker, Irwin, Maertens, Johan, Lewalle, Philippe, Olavarria, Eduardo, Selleslag, Dominik, Lachance, Sylvie, Buyse, Marc, Wang, Kun, Rovers, Jeroen, Santi, Irene, Bonig, Halvard, Sandler, Andrew, Velthuis, Jurjen, Mielke, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326707/
https://www.ncbi.nlm.nih.gov/pubmed/32047237
http://dx.doi.org/10.1038/s41375-020-0733-0