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Circular RNAs: Promising Molecular Biomarkers of Human Aging-Related Diseases via Functioning as an miRNA Sponge

Circular RNAs (circRNAs) are a new class of noncoding single-stranded RNAs that differ from linear microRNAs (miRNAs), since they form covalently closed loop structures without free 3′ poly(A) tails or 5′ caps. circRNAs are the competitive endogenous RNAs (ceRNAs) by binding to miRNA through miRNA r...

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Detalles Bibliográficos
Autores principales: Ren, Shuyue, Lin, Peirong, Wang, Jingrong, Yu, Haoying, Lv, Tingting, Sun, Lan, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326721/
https://www.ncbi.nlm.nih.gov/pubmed/32637451
http://dx.doi.org/10.1016/j.omtm.2020.05.027