Experimental Variables that Affect Human Hepatocyte AAV Transduction in Liver Chimeric Mice

Adeno-associated virus (AAV) vector serotypes vary in their ability to transduce hepatocytes from different species. Chimeric mouse models harboring human hepatocytes have shown translational promise for liver-directed gene therapies. However, many variables that influence human hepatocyte transduct...

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Detalles Bibliográficos
Autores principales: Zou, Chenhui, Vercauteren, Koen O.A., Michailidis, Eleftherios, Kabbani, Mohammad, Zoluthkin, Irene, Quirk, Corrine, Chiriboga, Luis, Yazicioglu, Mustafa, Anguela, Xavier M., Meuleman, Philip, High, Katherine A., Herzog, Roland W., de Jong, Ype P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326722/
https://www.ncbi.nlm.nih.gov/pubmed/32637450
http://dx.doi.org/10.1016/j.omtm.2020.05.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326722/
https://www.ncbi.nlm.nih.gov/pubmed/32637450
http://dx.doi.org/10.1016/j.omtm.2020.05.033

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