Cargando…

Systematic engineering of branch chain amino acid supply modules for the enhanced production of bacitracin from Bacillus licheniformis

Bacitracin is a broad-spectrum cyclic peptide antibiotic mainly produced by Bacillus, precursor amino acid supply served as the critical role during its synthesis. In this study, we systematically engineered branch-chain amino acid (BCAA) supply modules for bacitracin production. Firstly, we demonst...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Dongbo, Zhu, Jiang, Li, Yang, Li, Lingfeng, Zhang, Meng, Wang, Zhi, Yang, Hanbo, Li, Junhui, Yang, Zhifan, Chen, Shouwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326738/ https://www.ncbi.nlm.nih.gov/pubmed/32637317 http://dx.doi.org/10.1016/j.mec.2020.e00136

Ejemplares similares

Enhanced Bacitracin Production by Systematically Engineering S-Adenosylmethionine Supply Modules in Bacillus licheniformis
por: Cai, Dongbo, et al.
Publicado: (2020)

Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis
por: Zhu, Jiang, et al.
Publicado: (2018)

Microbial synthesis of bacitracin: Recent progress, challenges, and prospects
por: Zhu, Jiang, et al.
Publicado: (2023)

Rewiring glycerol metabolism for enhanced production of poly-γ-glutamic acid in Bacillus licheniformis
por: Zhan, Yangyang, et al.
Publicado: (2018)

Engineering Bacillus licheniformis for the production of meso-2,3-butanediol
por: Qiu, Yimin, et al.
Publicado: (2016)

Systematic mutagenesis method for enhanced production of bacitracin by Bacillus licheniformis Mutant Strain UV-MN-HN-6
por: Aftab, Muhammad Nauman, et al.
Publicado: (2012)

Global supply chains in the pandemic()
por: Bonadio, Barthélémy, et al.
Publicado: (2021)

Engineering Expression Cassette of pgdS for Efficient Production of Poly-γ-Glutamic Acids With Specific Molecular Weights in Bacillus licheniformis
por: Wang, Dong, et al.
Publicado: (2020)

Enhanced production of poly-γ-glutamic acid via optimizing the expression cassette of Vitreoscilla hemoglobin in Bacillus licheniformis
por: Zhang, Qing, et al.
Publicado: (2022)

A novel strategy to improve protein secretion via overexpression of the SppA signal peptide peptidase in Bacillus licheniformis
por: Cai, Dongbo, et al.
Publicado: (2017)

(13)C-Metabolic Flux Analysis Reveals the Metabolic Flux Redistribution for Enhanced Production of Poly-γ-Glutamic Acid in dlt Over-Expressed Bacillus licheniformis
por: He, Penghui, et al.
Publicado: (2019)

VaccineChain: A checkpoint assisted scalable blockchain based secure vaccine supply chain with selective revocation()
por: Mishra, Rahul, et al.
Publicado: (2023)

A novel approach to improve poly-γ-glutamic acid production by NADPH Regeneration in Bacillus licheniformis WX-02
por: Cai, Dongbo, et al.
Publicado: (2017)

Biochemical characteristics and potential application of a thermostable starch branching enzyme from Bacillus licheniformis
por: Yang, Ting, et al.
Publicado: (2023)

Metabolic Engineering of Bacillus licheniformis for Production of Acetoin
por: Lü, Chuanjuan, et al.
Publicado: (2020)

Effects of Flavomycin, Bacillus licheniformis and Enramycin on Performance, Nutrient Digestibility, Gut Morphology and the Intestinal Microflora of Broilers
por: Wang, Hong L., et al.
Publicado: (2016)

Effects of Bacillus subtilis and Bacillus licheniformis on growth performance, immunity, short chain fatty acid production, antioxidant capacity, and cecal microflora in broilers
por: Xu, Yinglei, et al.
Publicado: (2021)

Genetically encoded non‐canonical amino acids reveal asynchronous dark reversion of chromophore, backbone, and side‐chains in EL222
por: Chaudhari, Aditya S., et al.
Publicado: (2023)

Expression and Secretion of Cyan Fluorescent Protein (CFP) in B. subtilis using the Chitinase Promoter from Bacillus pumilus SG2
por: Shali, Abbas, et al.
Publicado: (2017)

Engineered multiple translation initiation sites: a novel tool to enhance protein production in Bacillus licheniformis and other industrially relevant bacteria
por: Zhang, Manyu, et al.
Publicado: (2022)

Bacillus licheniformis-Fermented Products Improve Growth Performance and Intestinal Gut Morphology in Broilers under Clostridium perfringens Challenge
por: Cheng, Yeong-Hsiang, et al.
Publicado: (2021)

Human viruses lurking in the environment activated by excessive use of COVID-19 prevention supplies
por: Hu, Zhichao, et al.
Publicado: (2022)

Recurrent Sepsis Due To Bacillus Licheniformis
por: Haydushka, Irina A, et al.
Publicado: (2012)

Enhanced production of iturin A by strengthening fatty acid synthesis modules in Bacillus amyloliquefaciens
por: Gao, Lin, et al.
Publicado: (2022)

Branched-chain Amino Acid Biosensing Using Fluorescent Modified Engineered Leucine/Isoleucine/Valine Binding Protein
por: Chino, Sakura, et al.
Publicado: (2007)

Biochemical Characterization of An Arginine-Specific Alkaline Trypsin from Bacillus licheniformis
por: Gong, Jin-Song, et al.
Publicado: (2015)

Deletion of meso-2,3-butanediol dehydrogenase gene budC for enhanced D-2,3-butanediol production in Bacillus licheniformis
por: Qi, Gaofu, et al.
Publicado: (2014)

Quantitative Proteomic Analysis of Cellular Responses to a Designed Amino Acid Feed in a Monoclonal Antibody Producing Chinese Hamster Ovary Cell Line
por: Torkashvand, Fatemeh, et al.
Publicado: (2018)

Bacitracin, Bacillus subtilis, and Eimeria spp. challenge exacerbates woody breast incidence and severity in broilers
por: Jia, Linan, et al.
Publicado: (2021)

Aerobic acetone-butanol-isopropanol (ABI) fermentation through a co-culture of Clostridium beijerinckii G117 and recombinant Bacillus subtilis 1A1
por: Cui, Yonghao, et al.
Publicado: (2020)

4H12, a Murine Monoclonal Antibody Directed against Myosin Heavy Chain-9 Expressed on Acinar Cell Carcinoma of Pancreas with Potential Therapeutic Application
por: Balouchi-Anaraki, Sima, et al.
Publicado: (2021)

Metabolic engineering enables Bacillus licheniformis to grow on the marine polysaccharide ulvan
por: Dutschei, Theresa, et al.
Publicado: (2022)

Medicaid expansion and opioid supply policies to address the opioid overdose crisis
por: Shakya, Shishir, et al.
Publicado: (2022)

Drug supply measures and drug overdose mortality in the era of fentanyl and stimulants
por: Cano, Manuel, et al.
Publicado: (2023)

Amino acid metabolism in skeletal cells
por: Devignes, Claire-Sophie, et al.
Publicado: (2022)

An efficient three-component, one-pot synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines in water
por: Li, Qiao-Yan, et al.
Publicado: (2012)

Copper at the crossroads: Assessment of the interactions between low-carbon energy transition and supply limitations
por: Seck, Gondia Sokhna, et al.
Publicado: (2020)

Improving decolorization of dyes by laccase from Bacillus licheniformis by random and site-directed mutagenesis
por: Bu, Tongliang, et al.
Publicado: (2020)

Effect of glucose on poly-γ-glutamic acid metabolism in Bacillus licheniformis
por: Yu, Wencheng, et al.
Publicado: (2017)

Serum amino acids quantification by plasmonic colloidosome-coupled MALDI-TOF MS for triple-negative breast cancer diagnosis
por: Han, Xinyue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cdod2dvadg3itr5ehbk91pkdmb