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BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy

Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients. Despite virus-specific T cells and neutralizing antibodies, BKPyV persi...

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Detalles Bibliográficos
Autores principales: Manzetti, Julia, Weissbach, Fabian H., Graf, Fabrice E., Unterstab, Gunhild, Wernli, Marion, Hopfer, Helmut, Drachenberg, Cinthia B., Rinaldo, Christine Hanssen, Hirsch, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326741/
https://www.ncbi.nlm.nih.gov/pubmed/32599557
http://dx.doi.org/10.1016/j.isci.2020.101257