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The Glutamate System as a Crucial Regulator of CNS Toxicity and Survival of HIV Reservoirs
Glutamate (Glu) is the most abundant excitatory neurotransmitter in the central nervous system (CNS). HIV-1 and viral proteins compromise glutamate synaptic transmission, resulting in poor cell-to-cell signaling and bystander toxicity. In this study, we identified that myeloid HIV-1-brain reservoirs...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326772/ https://www.ncbi.nlm.nih.gov/pubmed/32670889 http://dx.doi.org/10.3389/fcimb.2020.00261 |