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Exploiting CRISPR Cas9 in Three-Dimensional Stem Cell Cultures to Model Disease

Three-dimensional (3D) cell culture methods have been widely used on a range of cell types, including stem cells to modulate precisely the cellular biophysical and biochemical microenvironment and control various cell signaling cues. As a result, more in vivo-like microenvironments are recapitulated...

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Detalles Bibliográficos
Autores principales: Gopal, Sneha, Rodrigues, André Lopes, Dordick, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326781/
https://www.ncbi.nlm.nih.gov/pubmed/32671050
http://dx.doi.org/10.3389/fbioe.2020.00692