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Exploiting CRISPR Cas9 in Three-Dimensional Stem Cell Cultures to Model Disease
Three-dimensional (3D) cell culture methods have been widely used on a range of cell types, including stem cells to modulate precisely the cellular biophysical and biochemical microenvironment and control various cell signaling cues. As a result, more in vivo-like microenvironments are recapitulated...
Autores principales: | Gopal, Sneha, Rodrigues, André Lopes, Dordick, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326781/ https://www.ncbi.nlm.nih.gov/pubmed/32671050 http://dx.doi.org/10.3389/fbioe.2020.00692 |
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