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Peptide Folding and Binding Probed by Systematic Non-canonical Mutagenesis
Many proteins and peptides fold upon binding another protein. Mutagenesis has proved an essential tool in the study of these multi-step molecular recognition processes. By comparing the biophysical behavior of carefully selected mutants, the concert of interactions and conformational changes that oc...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326784/ https://www.ncbi.nlm.nih.gov/pubmed/32671094 http://dx.doi.org/10.3389/fmolb.2020.00100 |