Tet3 regulates cellular identity and DNA methylation in neural progenitor cells

TET enzymes oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), a process thought to be intermediary in an active DNA demethylation mechanism. Notably, 5hmC is highly abundant in the brain and in neuronal cells. Here, we interrogated the function of Tet3 in neural precursor cells (NP...

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Detalles Bibliográficos
Autores principales: Santiago, Mafalda, Antunes, Claudia, Guedes, Marta, Iacovino, Michelina, Kyba, Michael, Reik, Wolf, Sousa, Nuno, Pinto, Luísa, Branco, Miguel R., Marques, C. Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326798/
https://www.ncbi.nlm.nih.gov/pubmed/31646359
http://dx.doi.org/10.1007/s00018-019-03335-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326798/
https://www.ncbi.nlm.nih.gov/pubmed/31646359
http://dx.doi.org/10.1007/s00018-019-03335-7

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