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Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling

Adolescent alcohol exposure may increase anxiety-like behaviors by altering central monoaminergic functions and other important neuronal pathways. The present study was designed to investigate the anxiolytic effect of 0.5% γ-oryzanol (GORZ) and its neurochemical and molecular mechanisms under chroni...

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Detalles Bibliográficos
Autores principales: Akter, Salina, Uddin, Kazi Rasel, Sasaki, Hiroyuki, Lyu, Yijin, Shibata, Shigenobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326911/
https://www.ncbi.nlm.nih.gov/pubmed/32606350
http://dx.doi.org/10.1038/s41598-020-67689-w