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SnoRNA signatures in cartilage ageing and osteoarthritis

Osteoarthritis presents as a change in the chondrocyte phenotype and an imbalance between anabolic and catabolic processes. Age affects its onset and progression. Small nucleolar RNAs (SnoRNAs) direct chemical modification of RNA substrates to fine-tune spliceosomal and rRNA function, accommodating...

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Detalles Bibliográficos
Autores principales: Peffers, Mandy J., Chabronova, Alzbeta, Balaskas, Panagiotis, Fang, Yongxiang, Dyer, Philip, Cremers, Andy, Emans, Pieter J., Feczko, Peter Z., Caron, Marjolein M., Welting, Tim J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326970/
https://www.ncbi.nlm.nih.gov/pubmed/32606371
http://dx.doi.org/10.1038/s41598-020-67446-z