Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues

In continuation of our work on enzyme inhibition, the benzofuran-based-thiazoldinone analogues (1–14) were synthesized, characterized by HREI-MS, (1)H and (13)CNMR and evaluated for urease inhibition. Compounds 1–14 exhibited a varying degree of urease inhibitory activity with IC(50) values between...

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Detalles Bibliográficos
Autores principales: Taha, Muhammad, Rahim, Fazal, Ullah, Hayat, Wadood, Abdul, Farooq, Rai Khalid, Shah, Syed Adnan Ali, Nawaz, Muhammad, Zakaria, Zainul Amiruddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326984/
https://www.ncbi.nlm.nih.gov/pubmed/32606439
http://dx.doi.org/10.1038/s41598-020-67414-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326984/
https://www.ncbi.nlm.nih.gov/pubmed/32606439
http://dx.doi.org/10.1038/s41598-020-67414-7

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