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Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues

In continuation of our work on enzyme inhibition, the benzofuran-based-thiazoldinone analogues (1–14) were synthesized, characterized by HREI-MS, (1)H and (13)CNMR and evaluated for urease inhibition. Compounds 1–14 exhibited a varying degree of urease inhibitory activity with IC(50) values between...

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Detalles Bibliográficos
Autores principales:	Taha, Muhammad, Rahim, Fazal, Ullah, Hayat, Wadood, Abdul, Farooq, Rai Khalid, Shah, Syed Adnan Ali, Nawaz, Muhammad, Zakaria, Zainul Amiruddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326984/ https://www.ncbi.nlm.nih.gov/pubmed/32606439 http://dx.doi.org/10.1038/s41598-020-67414-7

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