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β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression

Increased endothelial cell (EC) apoptosis is associated with the development of atherosclerotic plaques that develop predominantly at sites exposed to disturbed flow (DF). Strategies to promote EC survival may therefore represent a novel therapeutic approach in cardiovascular disease. Nitric oxide (...

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Detalles Bibliográficos
Autores principales: Tajadura, Virginia, Hansen, Marie Haugsten, Smith, Joy, Charles, Hannah, Rickman, Matthew, Farrell-Dillon, Keith, Claro, Vasco, Warboys, Christina, Ferro, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326989/
https://www.ncbi.nlm.nih.gov/pubmed/32606304
http://dx.doi.org/10.1038/s41419-020-2687-6