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HSPG2 overexpression independently predicts poor survival in patients with acute myeloid leukemia

Heparan sulfate proteoglycan 2 (HSPG2), also known as perlecan, is a large multi-domain extracellular matrix proteoglycan, which contributes to the invasion, metastasis and angiogenesis of solid tumor. However, very little is known about the effect of HSPG2 on acute myeloid leukemia (AML). This stud...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaojia, Liang, Simin, Zhan, Qian, Yang, Li, Chi, Jianxiang, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327006/
https://www.ncbi.nlm.nih.gov/pubmed/32606327
http://dx.doi.org/10.1038/s41419-020-2694-7