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Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties

Recombinant adeno-associated viruses (rAAVs) are currently considered the safest and most reliable gene delivery vehicles for human gene therapy. Three serotype capsids, AAV1, AAV2, and AAV9, have been approved for commercial use in patients, but they may not be suitable for all therapeutic contexts...

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Detalles Bibliográficos
Autores principales: Hsu, Hung-Lun, Brown, Alexander, Loveland, Anna B., Lotun, Anoushka, Xu, Meiyu, Luo, Li, Xu, Guangchao, Li, Jia, Ren, Lingzhi, Su, Qin, Gessler, Dominic J., Wei, Yuquan, Tai, Phillip W. L., Korostelev, Andrei A., Gao, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327033/
https://www.ncbi.nlm.nih.gov/pubmed/32606306
http://dx.doi.org/10.1038/s41467-020-17047-1