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Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models

Tissue fibrosis underlies the majority of human mortality to date with close to half of all reported deaths having a fibrotic etiology. The progression of fibrosis is very complex and reputed irreversible once established. Although some preventive options are being reported, therapeutic options are...

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Detalles Bibliográficos
Autores principales: Nono, Justin Komguep, Fu, Kai, Mpotje, Thabo, Varrone, Georgianna, Aziz, Nada Abdel, Mosala, Paballo, Hlaka, Lerato, Kamdem, Severin Donald, Xu, Daigen, Spangenberg, Thomas, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327036/
https://www.ncbi.nlm.nih.gov/pubmed/32606340
http://dx.doi.org/10.1038/s41598-020-67514-4