Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic scarring disease in which aging, environmental exposure(s) and genetic susceptibility have been implicated in disease pathogenesis, however, the causes and mechanisms of the progressive fibrotic cascade are still poorly understood. As epithelial–mesen...

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Detalles Bibliográficos
Autores principales: Conforti, Franco, Ridley, Robert, Brereton, Christopher, Alzetani, Aiman, Johnson, Benjamin, Marshall, Ben G., Fletcher, Sophie V., Ottensmeier, Christian H., Richeldi, Luca, Skipp, Paul, Wang, Yihua, Jones, Mark G., Davies, Donna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327077/
https://www.ncbi.nlm.nih.gov/pubmed/32637156
http://dx.doi.org/10.1038/s41420-020-0289-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327077/
https://www.ncbi.nlm.nih.gov/pubmed/32637156
http://dx.doi.org/10.1038/s41420-020-0289-9

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