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Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic scarring disease in which aging, environmental exposure(s) and genetic susceptibility have been implicated in disease pathogenesis, however, the causes and mechanisms of the progressive fibrotic cascade are still poorly understood. As epithelial–mesen...
Autores principales: | Conforti, Franco, Ridley, Robert, Brereton, Christopher, Alzetani, Aiman, Johnson, Benjamin, Marshall, Ben G., Fletcher, Sophie V., Ottensmeier, Christian H., Richeldi, Luca, Skipp, Paul, Wang, Yihua, Jones, Mark G., Davies, Donna E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327077/ https://www.ncbi.nlm.nih.gov/pubmed/32637156 http://dx.doi.org/10.1038/s41420-020-0289-9 |
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