Natural Selection on Exonic SNPs Shapes Allelic Expression Imbalance (AEI) Adaptability in Lung Cancer Progression

Tumors are driven by a sequence of genetic and epigenetic alterations. Previous studies have mostly focused on the roles of somatic mutations in tumorigenesis, but how germline variants act is largely unknown. In this study, we hypothesized that allelic expression imbalance (AEI) participated in the...

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Detalles Bibliográficos
Autores principales: Huang, Jinfei, Zhang, Yuchao, Ma, Qingyang, Zhang, Yuhang, Wang, Meng, Zhou, You, Xing, Zhihao, Jin, Meiling, Hu, Landian, Kong, Xiangyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327089/
https://www.ncbi.nlm.nih.gov/pubmed/32670357
http://dx.doi.org/10.3389/fgene.2020.00665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327089/
https://www.ncbi.nlm.nih.gov/pubmed/32670357
http://dx.doi.org/10.3389/fgene.2020.00665

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