Exogenous Cardiac Bridging Integrator 1 Benefits Mouse Hearts With Pre-existing Pressure Overload-Induced Heart Failure

Background: Cardiac bridging integrator 1 (cBIN1) organizes transverse tubule (t-tubule) membrane calcium handling microdomains required for normal beat-to-beat contractility. cBIN1 is transcriptionally reduced in heart failure (HF). We recently found that cBIN1 pretreatment can limit HF development...

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Detalles Bibliográficos
Autores principales: Li, Jing, Agvanian, Sosse, Zhou, Kang, Shaw, Robin M., Hong, TingTing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327113/
https://www.ncbi.nlm.nih.gov/pubmed/32670093
http://dx.doi.org/10.3389/fphys.2020.00708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327113/
https://www.ncbi.nlm.nih.gov/pubmed/32670093
http://dx.doi.org/10.3389/fphys.2020.00708

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