Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A

Cytochrome P450 (CYP) 3A enzymes, the most important phase 1 drug-metabolizing enzymes, are responsible for 50% of the metabolism of clinically used drugs. CYP3A activity varies widely among individuals, which can affect the probability of adverse drug reactions and drug-drug interactions mediated b...

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Detalles Bibliográficos
Autores principales: Lee, Yujin, Chae, Woori, Yoon, Seonghae, Chung, Jae-Yong, Cho, Joo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327190/
https://www.ncbi.nlm.nih.gov/pubmed/32656158
http://dx.doi.org/10.12793/tcp.2020.28.e10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327190/
https://www.ncbi.nlm.nih.gov/pubmed/32656158
http://dx.doi.org/10.12793/tcp.2020.28.e10

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