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The passage from bone marrow niche to bloodstream triggers the metabolic impairment in Fanconi Anemia mononuclear cells

Fanconi Anemia (FA) is a disease characterized by bone marrow (BM) failure and aplastic anemia. In addition to a defective DNA repair system, other mechanisms are involved in its pathogenesis, such as defective mitochondrial metabolism, accumulation of lipids, and increment of oxidative stress produ...

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Detalles Bibliográficos
Autores principales: Cappelli, Enrico, Degan, Paolo, Bruno, Silvia, Pierri, Filomena, Miano, Maurizio, Raggi, Federica, Farruggia, Piero, Mecucci, Cristina, Crescenzi, Barbara, Naim, Valeria, Dufour, Carlo, Ravera, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327247/
https://www.ncbi.nlm.nih.gov/pubmed/32863220
http://dx.doi.org/10.1016/j.redox.2020.101618