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Iron regulates myeloma cell/macrophage interaction and drives resistance to bortezomib

Iron plays a major role in multiple processes involved in cell homeostasis such as metabolism, respiration and DNA synthesis. Cancer cells exhibit pronounced iron retention as compared to healthy counterpart. This phenomenon also occurs in multiple myeloma (MM), a hematological malignancy characteri...

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Detalles Bibliográficos
Autores principales: Camiolo, Giuseppina, Barbato, Alessandro, Giallongo, Cesarina, Vicario, Nunzio, Romano, Alessandra, Parrinello, Nunziatina L., Parenti, Rosalba, Sandoval, Joaquín Cantón, García-Moreno, Diana, Lazzarino, Giacomo, Avola, Roberto, Palumbo, Giuseppe A., Mulero, Victoriano, Li Volti, Giovanni, Tibullo, Daniele, Di Raimondo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327252/
https://www.ncbi.nlm.nih.gov/pubmed/32863212
http://dx.doi.org/10.1016/j.redox.2020.101611