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Astrocytic histone deacetylase 2 facilitates delayed depression and memory impairment after subarachnoid hemorrhage by negatively regulating glutamate transporter-1

BACKGROUND: Delayed cognitive impairment (DCI) after subarachnoid hemorrhage (SAH) is one of the most common sequelae in patients. This study aimed to investigate the characteristics of the course and glutamatergic pathogenesis of DCI after SAH in mice. METHODS: A SAH mouse model of internal carotid...

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Detalles Bibliográficos
Autores principales: Tao, Kai, Cai, Qing, Zhang, Xudong, Zhu, Lin, Liu, Zhenru, Li, Fei, Wang, Qiang, Liu, Lei, Feng, Dayun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327310/
https://www.ncbi.nlm.nih.gov/pubmed/32617311
http://dx.doi.org/10.21037/atm-20-4330