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Urinary Concentration Defect and Renal Glycosuria in Cyclosporine-treated Rats
BACKGROUND: Urinary concentration impairment is a major feature of cyclosporine nephrotoxicity. METHODS: We explored two possible mechanisms that may underlie cyclosporine-induced polyuria; water, and/or osmotic diuresis. Cyclosporine was subcutaneously injected to normal salt-fed Sprague-Dawley rat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Society of Electrolyte Metabolism
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327388/ https://www.ncbi.nlm.nih.gov/pubmed/32655650 http://dx.doi.org/10.5049/EBP.2020.18.1.1 |