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MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells

Irreversible blindness from glaucoma and optic neuropathies is attributed to retinal ganglion cells (RGCs) losing the ability to regenerate axons. While several transcription factors and proteins have demonstrated enhancement of axon regeneration after optic nerve injury, mechanisms contributing to...

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Detalles Bibliográficos
Autores principales: Mak, Heather K., Yung, Jasmine S.Y., Weinreb, Robert N., Ng, Shuk Han, Cao, Xu, Ho, Tracy Y.C., Ng, Tsz Kin, Chu, Wai Kit, Yung, Wing Ho, Choy, Kwong Wai, Wang, Chi Chiu, Lee, Tin Lap, Leung, Christopher Kai-shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327411/
https://www.ncbi.nlm.nih.gov/pubmed/32599451
http://dx.doi.org/10.1016/j.omtn.2020.05.031