Electron microscopy-based semi-automated characterization of aggregation in monoclonal antibody products

Aggregation is a critical parameter for protein-based therapeutics, due to its impact on the immunogenicity of the product. The traditional approach towards characterization of such products is to use a collection of orthogonal tools. However, the fact that none of these tools is able to completely...

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Detalles Bibliográficos
Autores principales: Kumar, Mohit, Pant, Apoorv, Bansal, Rohit, Pandey, Ashutosh, Gomes, James, Khare, Kedar, Singh Rathore, Anurag, Banerjee, Manidipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327430/
https://www.ncbi.nlm.nih.gov/pubmed/32637043
http://dx.doi.org/10.1016/j.csbj.2020.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327430/
https://www.ncbi.nlm.nih.gov/pubmed/32637043
http://dx.doi.org/10.1016/j.csbj.2020.06.009

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