Cargando…
Electron microscopy-based semi-automated characterization of aggregation in monoclonal antibody products
Aggregation is a critical parameter for protein-based therapeutics, due to its impact on the immunogenicity of the product. The traditional approach towards characterization of such products is to use a collection of orthogonal tools. However, the fact that none of these tools is able to completely...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327430/ https://www.ncbi.nlm.nih.gov/pubmed/32637043 http://dx.doi.org/10.1016/j.csbj.2020.06.009 |