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SUMOylated PRC1 controls histone H3.3 deposition and genome integrity of embryonic heterochromatin

Chromatin integrity is essential for cellular homeostasis. Polycomb group proteins modulate chromatin states and transcriptionally repress developmental genes to maintain cell identity. They also repress repetitive sequences such as major satellites and constitute an alternative state of pericentrom...

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Detalles Bibliográficos
Autores principales: Liu, Zichuan, Tardat, Mathieu, Gill, Mark E, Royo, Helene, Thierry, Raphael, Ozonov, Evgeniy A, Peters, Antoine HFM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327501/
https://www.ncbi.nlm.nih.gov/pubmed/32395866
http://dx.doi.org/10.15252/embj.2019103697