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Yeast Spt6 Reads Multiple Phosphorylation Patterns of RNA Polymerase II C-Terminal Domain In Vitro

Transcription elongation factor Spt6 associates with RNA polymerase II (RNAP II) via a tandem SH2 (tSH2) domain. The mechanism and significance of the RNAP II–Spt6 interaction is still unclear. Recently, it was proposed that Spt6-tSH2 is recruited via a newly described phosphorylated linker between...

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Detalles Bibliográficos
Autores principales: Brázda, Pavel, Krejčíková, Magdaléna, Kasiliauskaite, Aiste, Šmiřáková, Eliška, Klumpler, Tomáš, Vácha, Robert, Kubíček, Karel, Štefl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327521/
https://www.ncbi.nlm.nih.gov/pubmed/32439331
http://dx.doi.org/10.1016/j.jmb.2020.05.007