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Non-adherence in non-inferiority trials: pitfalls and recommendations

Non-adherence in non-inferiority trials can affect treatment effect estimates and often increases the chance of claiming non-inferiority under the standard intention-to-treat analysis. This article discusses the implications of different patterns of non-adherence in non-inferiority trials and offers...

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Detalles Bibliográficos
Autores principales: Mo, Yin, Lim, Cherry, Watson, James A, White, Nicholas J, Cooper, Ben S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327542/
https://www.ncbi.nlm.nih.gov/pubmed/32611541
http://dx.doi.org/10.1136/bmj.m2215