Transforming activities of the NUP98-KMT2A fusion gene associated with myelodysplasia and acute myeloid leukemia

Inv(11)(p15q23), found in myelodysplastic syndromes and acute myeloid leukemia, leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A). To explore the transforming potential of this fusion we establis...

Descripción completa

Detalles Bibliográficos
Autores principales: Fisher, James N., Thanasopoulou, Angeliki, Juge, Sabine, Tzankov, Alexandar, Bagger, Frederik O., Mendez, Max A., Peters, Antoine H.F.M., Schwaller, Juerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327646/
https://www.ncbi.nlm.nih.gov/pubmed/31558671
http://dx.doi.org/10.3324/haematol.2019.219188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327646/
https://www.ncbi.nlm.nih.gov/pubmed/31558671
http://dx.doi.org/10.3324/haematol.2019.219188

Ejemplares similares