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Hypoxia-inducible factor-1α in acute ischemic stroke: neuroprotection for better clinical outcome

BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor which maintains cellular homeostasis in response to hypoxia. It can trigger apoptosis while stimulating angiogenesis process and decrease neurological deficit after an ischemic stroke. Up until now, this protein complex has n...

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Detalles Bibliográficos
Autores principales: Amalia, Lisda, Sadeli, Henny Anggraini, Parwati, Ida, Rizal, Ahmad, Panigoro, Ramdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327744/
https://www.ncbi.nlm.nih.gov/pubmed/32637689
http://dx.doi.org/10.1016/j.heliyon.2020.e04286