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Assembling structurally customizable synthetic carriers of siRNA through thermodynamically self-regulated process

This study demonstrates that our previously reported polywraplex, a synthetic siRNA carrier consisting of a uni-molecular polyplex core of customizable size and a self-assembled tri-block copolymer envelop, may be constructed using dendrimers as the crosslinking junctions. Replacing the branched low...

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Detalles Bibliográficos
Autores principales: Bai, Guang, Xue, Tong, Dong, Xiaotao, Chinta, Uday Kumar, Feng, Jia, Jin, Tuo, Wu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327762/
https://www.ncbi.nlm.nih.gov/pubmed/32636953
http://dx.doi.org/10.1016/j.ajps.2019.04.008