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Intranasal delivery of paeoniflorin nanocrystals for brain targeting

Paeoniflorin (PA) is an anti-Parkinson Chinese medicine with inferior bioavailability and difficulty in delivery to the brain. This research is to develop an efficacious PA nanocrystal formulation (PA-NCs) that is suitable for intranasal administration to treat Parkinson's disease (PD). PA-NCs...

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Detalles Bibliográficos
Autores principales: Wu, Chaoyin, Li, Benyue, Zhang, Yi, Chen, Tingting, Chen, Chuangrong, Jiang, Wei, Wang, Qi, Chen, Tongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327772/
https://www.ncbi.nlm.nih.gov/pubmed/32636950
http://dx.doi.org/10.1016/j.ajps.2019.11.002