Site directed mutagenesis as a precision tool to enable synthetic biology with engineered modular polyketide synthases
Modular polyketide synthases (PKSs) are a multidomain megasynthase class of biosynthetic enzymes that have great promise for the development of new compounds, from new pharmaceuticals to high value commodity and specialty chemicals. Their colinear biosynthetic logic has been viewed as a promising pl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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KeAi Publishing
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327777/ https://www.ncbi.nlm.nih.gov/pubmed/32637664 http://dx.doi.org/10.1016/j.synbio.2020.04.001 |