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A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice

BACKGROUND & AIMS: In short-bowel syndrome (SBS), inadequate intestinal adaptation is responsible for the majority of complications, including sepsis, liver failure, and death. In this study, we sought to further delineate the adaptive response to identify potential therapeutic targets. METHODS:...

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Detalles Bibliográficos
Autores principales: Zhang, Ailan, Sodhi, Chhinder P., Wang, Menghan, Shores, Darla R., Fulton, William, Prindle, Thomas, Brosten, Serena, O’Hare, Elizabeth, Lau, Alexander, Ding, Hua, Jia, Hongpeng, Lu, Peng, White, James R., Hui, Justin, Sears, Cynthia L., Hackam, David J., Alaish, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327842/
https://www.ncbi.nlm.nih.gov/pubmed/32330729
http://dx.doi.org/10.1016/j.jcmgh.2020.04.006